Eight Great Ketogenic Diet Benefits

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As research and public awareness into the ketogenic diet continues to expand, we are learning more about the incredibly powerful benefits of ketones for health, wellness and treating disease. That said, many questions remain, especially for those who are new to the ketogenic diet and looking to get started. In this post, we take an introductory look at ketones and explore some of the top ketogenic diet benefits.

Heads Up Health is a free program to help you track all your health metrics – including ketones. You can sign up for free using the button below. Or, read on for our “Eight Great Ketogenic Diet Benefits”.

A Tale of Two Fuel Sources

Over the course of millions of years of evolution, our bodies have developed the ability to run off of two primary fuel sources – fat and glucose (carbohydrates). When we consume a diet that is abundant in carbohydrates, the body breaks down the carbohydrates into glucose, which becomes the primary fuel source for the cells in our body.

Conversely, when we consume a diet that is abundant in fat (and low in carbs), our cells can switch over and start metabolizing fat for energy.

Lastly, in periods of calorie restriction (starvation, intermittent fasting, high-intensity or ultra-endurance exercise etc.), our body will first burn off all our internal glucose reserves to fuel itself. If food is still not available, the body will then start burning its fat stores for energy.


Optimal calorie structure for the ketogenic diet

Optimal calorie structure for the ketogenic diet

When we burn fat for energy, either through a low-carb/high-fat diet or calorie restriction, the body produces ketones. Ketones, as we are now learning, are incredibly powerful compounds for optimal human health.

Rediscovering Our Fat Burning Machinery

In more recent times, our fat-burning fuel system has become obsolete. We live in a society where we have unlimited access to cheap and abundant food sources based almost entirely on carbohydrates (bread, pasta, grains, cereal, rice, sugar, corn, alcohol, fruit etc.). One consequence of relying almost exclusively on glucose for fuel and never accessing our fat stores for energy is that our fat stores just continue to grow, and grow, and grow. This comes with a host of health risks which are now plaguing our society such as obesity, diabetes, Alzheimer’s disease, cancer and heart disease to name just a few.

With the ketogenic diet, we are re-discovering our body’s ability to burn fat for energy. Whereas in the past this capability was used to help us survive and adapt to conditions where food (and carbs) were scarce, we are now learning how to strategically use this system to produce ketones for optimal health. We’ve had this ability for millions of years but somewhere along the line we lost touch with it. As it turns out, the cells in our body actually run better on ketones than they do on carbs.

Ketogenic Diet Benefits

With a basic understanding of ketones under our belt, we can now look at some of the top ketogenic diet benefits.

  1. Increased mental clarity:
    • Ketones pass directly through the blood-brain barrier and are a preferred fuel source for our brains. In fact, by some estimates, our brains may perform up to 25-30% more efficiently when running on ketones over carbohydrate [1]. The result is increased mental clarity, better focus and an overall sense of mental sharpness.


      Ketogenic diet benefits – our brains run better on ketones

  2. Increased energy levels:
    • The mitochondria are the power plants that produce energy in every cell in our body. Much like our brains, our mitochondria have evolved to be more efficient when burning fat (in the form of ketones) over carbs. With a more efficient fuel source for our mitochondria, ketones can provide a steady boost in our energy levels.

      Ketogenic diet benefits - increased mitochondrial energy

      Ketogenic diet benefits – increased mitochondrial energy

  3. Appetite regulation:
    • Ketones work in the body as a natural appetite suppressant. The exact mechanisms are not yet fully understood, but early research suggests that ketones signal to the brain we are in a fed state, thereby reducing appetite and food cravings.
  4. Weight loss:
    • As we enter a state of ketosis, we are reprogramming the cells in our body to burn fat (instead of carbs) for energy. This forces the body to dip into its fat reserves and burn the fat as energy. This is part of the reason why the ketogenic diet is so effective as a natural treatment for losing weight, treating obesity and improving body composition.

      Ketogenic Diet Benefits - Weight Loss

      Ketogenic Diet Benefits – Weight Loss

  5. Reduced inflammation:
    • Ketones reduce inflammation by directly inhibiting NLRP3, which is part of a complex set of proteins called the inflammasome. The inflammasome drives the inflammatory response in several disorders including autoimmune diseases, type 2 diabetes, Alzheimer’s disease, atherosclerosis, and auto-inflammatory disorders.[2]
  6. Lower blood sugar:
    • Ketones are a natural mechanism to reduce insulin and blood sugar. The ketogenic diet is also very low in carbs, which keeps blood sugar and insulin down. As a result, the ketogenic diet (and other low-carb/high-fat diets) can be an effective and natural strategy for treating (and reversing) conditions such as type 2 diabetes, obesity, Alzheimer’s and other metabolic conditions.
  7. Cancer treatment and prevention:
    • There are a number of studies currently underway exploring the ketogenic diet for cancer treatment [3]. The presence of ketones seems to inhibit the growth of cancer cells [4]. Additionally, since many types of cancer cells can only survive with glucose as a fuel source, we may be able to starve cancer cells through a low-carb/high-fat diet where ketones become the primary fuel source in the body.
  8. Disease management:
    • The ketogenic diet has also been used effectively as a treatment for epilepsy, polycystic ovarian syndrome (PCOS), irritable bowel syndrome (IBS), heartburn (GERD), nonalcoholic fatty liver disease (NAFLD), brain injury, dementia and many more.

Are Ketones Safe?

Although many conventional doctors and health professionals may not be up-to-speed on the latest research into ketogenic diets and the health benefits of ketones, the diet, when used properly, is a safe and effective strategy for improving health and treating a host of “western” diseases. In fact, given all of the health challenges and chronic diseases now being linked to the Standard American Diet, the ketogenic diet (and other low-carb/high-fat approaches) may actually be a safer and more effective nutritional strategy for optimal health.

Ketone bodies are produced in the liver when the body burns fat for energy

Ketone bodies are produced in the liver when the body burns fat for energy

The diet does come with its own set of challenges and it can be very difficult to implement and maintain. If you prefer to work with a professional, seek out a doctor or health professional who has expertise in the ketogenic diet and who can guide you along the way (see appendix for recommendations).

How to Generate Ketones for Your Health

There are two primary methods to obtain the benefits of ketones for your own health:

  1. Follow a ketogenic diet (nutritional ketosis): By following a diet that is high in fat, modest in protein and low in carbohydrate, we can naturally induce our body to start burning fat for fuel and producing ketones.
  2. Take ketone supplements (therapeutic ketosis): A second option is to consume ketones in the form of a supplement. Supplements provide the exact same ketone bodies that are produced naturally in the body. And while supplements are not a complete replacement for the benefits of ketones produced through diet, they do lower the barrier by allowing anyone to start benefiting from therapeutic ketones.

Hybrid strategy: A hybrid strategy is to follow a low-carb/high-fat ketogenic diet to induce nutritional ketosis and use ketone supplements strategically. Supplements can help ease the transition into ketosis, they can be an effective tool when we are knocked out of nutritional ketosis and they can help push ketone levels higher in the body for added benefit.

Like many aspects of human health, results will vary from person to person with ketone supplements. As research continues into these products, we will get a better understanding of how to best use them. For now, we recommend testing them out for yourself. There are several brands on the market. Heads Up Health has been testing the Keto O/S product with excellent results. Order a 3-pack sample from the link below and see how your feel!

Ketogenic diet benefits - ketone supplements

Track Your Progress

Heads Up Health was designed to help you track all of your health metrics in one place. Everything from weight readings to ketone values to cholesterol levels can be tracked within the app.

The video below is a short tutorial on how to use Heads Up Health for tracking ketones:

We also give you tools to look at trends over time, correlate different metrics and share your data with any health expert you choose. The graph below is showing weight and ketone readings graphed together in Heads Up Health to see how ketosis is affecting weight loss.

Ketogenic diet benefits - weight loss

Correlating weight and ketone readings in Heads Up Health


The ketogenic diet triggers a natural process in our body where we metabolize fat for fuel as opposed to glucose. A benefit of fat metabolization is the production of ketones – which offer a number of powerful benefits for human health. We are just now re-discovering this fat burning capability and learning how we can use ketones and the ketogenic diet to affect a number of powerful health outcomes.

For more information on getting started, check out our blog post: 5 Steps to Jumpstart the Ketogenic Diet. You can also sign up to Heads Up Health below and start tracking all your health metrics as you make the switch to a ketogenic diet. If you have any questions, feel free to shoot us an e-mail.



[1] http://www.drmyhill.co.uk/wiki/Ketogenic_diet_-_a_connection_between_mitochondria_and_diet

[2] http://www.ncbi.nlm.nih.gov/m/pubmed/25686106/?i=3&from=bhb+inflammation

[3] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215472/

[4] http://www.ncbi.nlm.nih.gov/pubmed/24615175


About the Author

Dave Korsunsky is a technologist and health tracking enthusiast. He is also the founder and CEO of Heads Up Health.

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